Ionis Pharmaceuticals, Inc. (IONS) fair value analysis
Nasdaq · Updated 2026-10-19
IONS price how computed
Valuation status
No fair-value estimate yetIONS has no usable analyst consensus for next fiscal year's earnings, or too few reported quarters for our trailing P/E history.
Forward Fair Value needs both, so TickrTrends publishes no verdict for IONS yet. We re-check every week; the price, fundamentals, technicals and earnings data below are unaffected.
- Last price
- $42.94
- Sector
- Healthcare
- 12-month range
- $42.38–$86.50
- Market cap
- $7.14B
- From 52-week high
- -50.4%
- Shares outstanding
- 166M
- Rank in Healthcare by quality score
- #144 of 301
Last price is the 2026-10-16 close; the chart runs through 2026-10-16.
Ionis Pharmaceuticals, Inc. is a biotechnology company that develops and commercializes antisense oligonucleotide drugs designed to treat various diseases by targeting and modulating specific genes. The company operates globally, with research and development activities based in the United States and commercial operations serving patients internationally.
IONS currently ranks #144 of 301 Healthcare stocks by quality score.
Fundamentals (4 quarters) how computed
- Market cap
- $7.14B
- P/E (trailing)
- n/m
- Revenue (TTM)
- $874M
- Net margin
- -64.6%
- EPS (TTM)
- $-2.76
- Gross margin
- 99.0%
- Debt / equity
- 5.50
- Revenue growth (3-yr avg)
- 28.6%
- Shares outstanding
- 166M
Derived indicators how computed
- Quality grade
- D
- Margin trend
- Stable
- 52-week position
- The bottom quarter of its range
Technicals how computed
- RSI (14-day)
- 40 · neutral
- 50-day average
- $51.73
- 200-day average
- $68.60
- Moving-average state
- 50-day below 200-day (death cross state); price below both averages
Dividends how computed
- Dividend
- None in the last 12 months (last ex-date 2000-05-10)
Earnings how computed
- Next earnings report
- 2026-11-04
- Last 8 quarters vs consensus
- 8 beat, 0 missed
- Quarter by quarter
- 2026-06 ▲ beat (+35.8%)
2026-03 ▲ beat (+61.0%)
2025-12 ▲ beat (+13.7%)
2025-09 ▲ beat (+41.9%)
2025-06 ▲ beat (+431.2%)
2025-03 ▲ beat (+10.7%)
2024-12 ▲ beat (+49.0%)
2024-09 ▲ beat (+18.1%)
Analyst consensus how computed
This is not TickrTrends' verdict.
- Analyst ratings
- 19 buy · 5 hold · 0 sell (24 analysts)
- Consensus lean
- Buy-leaning
- Consensus price target
- $83.8
- Target vs last price
- +95.2%
What our data shows for IONS
- Shares are trading in the lower third of their 12-month price range of $42.38–$86.50.
- The 14-day relative strength index sits at a neutral 40.
What subscribers see
- Every published Forward Fair Value with its exact discount or premium
- The normalized P/E and quarter count behind each estimate
- Screeners and rankings across the full S&P 500 and Nasdaq universes
- IONS's own verdict the week it qualifies, published automatically
Forward Fair Value applies a conservatively normalized historical price-to-earnings multiple to the consensus earnings estimate for the next full fiscal year; how TickrTrends computes it.
What people are saying
Follow the IONS conversation: Stocktwits · Reddit · X
TickrTrends weekly updates
- 2026-10-19 — No material change this week: the verdict, bands and grades all held steady.
- 2026-10-12 — No material change this week: the verdict, bands and grades all held steady.
- 2026-10-11 — No material change this week: the verdict, bands and grades all held steady.
- 2026-10-10 — TickrTrends' derived indicators for IONS showed notable shifts this week within the Healthcare sector. The quality grade declined from B to D, while the relative strength index zone moved from oversold to neutral conditions. The current valuation verdict remains awaiting full valuation.
- 2026-10-06 — No material change this week: the verdict, bands and grades all held steady.
- 2026-10-05 — No material change this week: the verdict, bands and grades all held steady.
- 2026-09-28 — TickrTrends initiated weekly Forward Fair Value coverage of this stock.
Frequently asked questions
Is IONS stock undervalued?
TickrTrends has no fair-value estimate for IONS yet: there is no usable analyst consensus for next fiscal year's earnings, or too few reported quarters for a trailing P/E history. It is re-checked every week.
What is IONS's TickrTrends verdict?
IONS is currently marked 'No fair-value estimate yet' - a verdict publishes automatically once a forward earnings consensus and enough reported quarters are available.
How does IONS compare to other Healthcare stocks?
IONS ranks #144 of 301 Healthcare stocks in TickrTrends' coverage by quality score. It carries no fair-value verdict yet, so it is not ranked by discount.
Is IONS overbought or oversold?
IONS's 14-day RSI is in neutral territory - neither overbought nor oversold.
Does IONS pay a dividend?
IONS has paid no dividend in the last twelve months; its last ex-dividend date on file was 2000-05-10.
When does IONS report earnings next?
IONS's next earnings report is scheduled for 2026-11-04, per the published earnings calendar.
Does IONS usually beat earnings estimates?
Over its last 8 reported quarters IONS beat the consensus estimate 8 times and missed 0 times, by TickrTrends' comparison of reported and estimated EPS.
What do analysts say about IONS?
Of 24 analysts covering IONS, 19 rate it a buy, 5 a hold and 0 a sell - buy-leaning, with a consensus price target of $83.8 (+95.2% versus TickrTrends' last price). This is the analyst consensus, not TickrTrends' Forward Fair Value verdict.